姓名：

沈如伟

性别：

男

出生年月：

1981.12

籍贯：

浙江

职称：

副教授

E-mail：

shenrw@njtech.edu.cn

工作地点：

弘毅楼C601/C615

学习工作经历

2004-2009 浙江大学化学系 博士

2009-2011 日本国家产业技术综合研究所 博士后

2011-2012 日本大阪大学工学院 博士后

2012-至今 伟德bevictor(中国)有限公司 教师

研究方向

精细有机合成、绿色合成工艺、金属催化、有机磷化学等。

代表性成果

(1) Zhang, C.; Li, J.; Wang, X.; Shen, X.; Zhu, D.; Shen, R.* Metal-Free Synthetic Shortcut to Octahydro-Dipyrroloquinoline Skeletons from 2,5-Cyclohexadienone Derivatives and L-Proline. J. Org. Chem. 2021, 86 (15), 10397–10406.

(2) Wang, X.; Li, G.; Li, X.; Zhu, D.; Shen, R.* One-Pot Three-Component Reaction of: P-Quinone Monoacetals, L-Proline and Naphthols to Afford N-Aryl-2-Arylpyrrolidines. Org. Chem. Front. 2021, 8 (2), 297–303.

(3) Wang, X.; Zhang, C.; Shen, R.*; Han, L.-B. Three-Component Reactions of α-Amino Acids, p-Quinone Monoacetals, and Diarylphosphine Oxides to Selectively Afford 3-(Diarylphosphinyl)Anilides and N-Aryl-2-Diarylphosphinylpyrrolidines. J. Org. Chem. 2020, 85 (22), 14753–14762. (Invited contribution)

(4) Shen, R.*; Wang, X.; Zhang, S.; Dong, C.; Zhu, D.; Han, L. B. Three-Component Reaction of p-Quinone Monoacetals, Amines and Diarylphosphine Oxides to Afford m-(Phosphinyl)Anilides. Adv. Synth. Catal. 2020, 362 (4), 942–948.

(5) Dong, C.; Wang, X.; Pei, Z.; Shen, R.* Metal-Free Denitrogenative C-C Couplings of Pyridotriazoles with Boronic Acids to Afford α-Secondary and α-Tertiary Pyridines. Org. Lett. 2019, 21 (11), 4148–4152.

(6) Zhang, M.; Jia, X.; Zhu, H.; Fang, X.; Ji, C.; Zhao, S.; Han, L.-B.; Shen, R.* Zinc-Catalyzed Regioselective C–P Coupling of p-Quinol Ethers with Secondary Phosphine Oxides to Afford 2-Phosphinylphenols. Org. Biomol. Chem. 2019, 17 (11), 2972–2984.

(7) Xiao, J.; Li, Q.; Shen, R.*; Shimada, S.; Han, L. B.* Phosphonium Phenolate Zwitterion vs Phosphonium Ylide: Synthesis, Characterization and Reactivity Study of a Trimethylphosphonium Phenolate Zwitterion. Adv. Synth. Catal. 2019, 361 (24), 5715–5720.

(8) Yang, J.; Wu, Y.; Zhang, M.; Zhu, D.; Shen, R.* Gold-Catalyzed Cycloisomerization of 2-Aryl-2-(Arylamino)-3-Butyn-1-Ols toward 2-(2′-Aminoaryl)-2,5-Dihydrofurans. Adv. Synth. Catal. 2018, 360 (10), 2043–2048.

(9) Zhang, M.; Yang, J.; Xu, Q.; Dong, C.; Han, L. B.; Shen, R.* Copper-Catalyzed Dehydrative Cyclization of 1-(2-Hydroxyphenyl)Propargyl Alcohols with P(O)H Compounds for the Synthesis of 2-Phosphorylmethylbenzofurans. Adv. Synth. Catal. 2018, 360 (2), 334–345.

(10) Shen, R.*; Zhang, M.; Xiao, J.; Dong, C.; Han, L. B.* Ph3P-Mediated Highly Selective C(α)-P Coupling of Quinone Monoacetals with R₂P(O)H: Convenient and Practical Synthesis of: Ortho-Phosphinyl Phenols. Green Chem. 2018, 20 (22), 5111–5116.